Development and validation for the simultaneous estimation of olmesartan medoxomil and hydrochlorothiazide by using RP-HPLC methods
نویسندگان
چکیده
A simple, Accurate, precise method was developed for the simultaneous estimation of Olmesartan Medoxomil and Hydrochlorothiazide in Tablet dosage form. Chromatogram run through Inertsil -ODS C18,250 x 4.6 mm, 5m. Mobile phase containing Methanoland Bufferin ratio 80:20 pumped column at a flow rate 10ml/min. Optimized wavelength Hydrochlorothiazidewas 260nm. Retention time Medoxomiland were found to be 3.270min 4.566 min. %assay obtained as 99.91% 99.95% respectively. Regression equation Medoxomilis y = 30712x - 31891, 16499x + 8683. Of Hydrochlorothiazide.
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ژورنال
عنوان ژورنال: World Journal Of Advanced Research and Reviews
سال: 2023
ISSN: ['2581-9615']
DOI: https://doi.org/10.30574/wjarr.2023.17.2.0247